PS128™ Pure Happiness
Prof. Tsai Ying-Chieh, an authority on probiotics in Asia, led the R&D team in Taiwan and Japan. They have devoted themselves to research in the field of probiotics for more than 20 years, accumulated solid professional academic research, and developed a unique happy probiotic from nearly a thousand of bacteria strains after a rigorous screening process. Professor Tsai Ying-Chieh said that the research and development technology of probiotics has entered a fairly mature era of specialized strain functions, which can be divided into four generations. The third generation is the regulation of metabolic functions, while the fourth generation is the latest research on physical and mental maintenance functions.

Won the global multi-national patent certification
PS128™ strain applies the research results of “bacteria-gut-brain axis” to the development of functional probiotics, and leads the industry to bring probiotics from the maintenance of digestive tract function (the first generation) to the field of physical and mental health care ( Fourth Generation). At present, it has obtained 26 patent certifications in 17 countries.
List of patents and countries
|
nation |
Patent size |
|
Taiwan |
I509070/I623318/I623319 |
|
China |
CN105002109B |
|
Japan |
Charter No. 6035578 |
|
South Korea |
10-1813881 |
|
U.S. |
US10188684B2 |
|
EU 14 |
EP2937424B1 |
The research team of Yang Ming University confirmed that PS128™ has a positive effect on stress regulation, and many research results have been published in top international journals 1-6 . Long-term and continuous consumption can adjust body quality, maintain pleasure, help fall asleep, and enhance physical strength.

Partners in more than 27 countries around the world
Since its launch, PS128™ Happy Probiotics has attracted much attention in the international biomedical field. Following Hong Kong, France, the United States and other markets, in 2019, it signed cooperation with major health food manufacturers in Singapore and Malaysia to advance Taiwan’s biotechnology industry The new Southbound market has reached another milestone and has become the light of Taiwan’s probiotics industry. Currently, it has partners in more than 27 countries around the world, and is deeply loved by consumers from all over the world.

International awards
In 2018, PS128™ won the “2018 Taipei Biotechnology Award” and the “Best Probiotic Product of the Year” award in the Nutra Ingredients-Asia Awards, which is known as the Oscar of the health food industry. The international exhibition sets a new milestone for probiotics in the field of health care, and more successfully brings Taiwan’s solid R&D achievements to the international medical stage.

User testimonials
“PS128 TM allows me to regain the joy of life after giving birth ” 39-year-old international law firm operator
When the postpartum depression started, I thought it was just a setback caused by poor milking, but the depression gradually became more serious. I lost interest in everything, even work. At the suggestion of a friend, I tried the PS128 TM . After two weeks of eating, I can clearly feel the improvement of the defecation problem that has been troubled for a long time, the sleep time is gradually extended, and the spirit is better during the day; after a month of eating, the motivation for work is obviously restored, and life begins to show a positive cycle. Thanks to Happy Probiotics, I have regained my most important family and work.
[ Body and Mind Balance – Stress Relief ] Yoga Teacher – Joey
I used to work in the advertising industry, with long working hours, high performance pressure, and a life that was upside down day and night, which deeply affected my life, and made my personality become impatient and harsh… In order to regain the balance of body and mind, I switched tracks, devoted myself to yoga teaching, and started using PS128 TM probiotics under the introduction of my students. After using it for more than two months, I found that PS128 TM probiotics can make me relax and focus at the same time, and make me more courageous to take on challenges , even if the stroke is full, it can remain calm and confident.
I also often recommend students to use Happy Probiotics, it keeps me happy and full of energy, I hope more people can benefit!
” PS128 TM makes it easy for me to solve sleep problems” 82 -year-old retired male
In the past few decades, I wanted to sleep at night, but my mind was clear and there was no sleepiness. Even when I fell asleep, I couldn’t get enough rest, which was very disturbing. I have tried many relaxation methods, but the situation has not improved much. Through a friend’s recommendation, after I started to use PS128 TM probiotics for a while, I can clearly feel that it can help you fall asleep, relax and sleep well, and you can get a good rest at night. When you wake up the next day, you will be full of energy, which will greatly improve the overall quality of life. And the body did not feel any discomfort, thank the research team again.
PS128 Published Studies
1 Liao, JF, et al. Lactobacillus plantarum PS128 ameliorates 2,5-Dimethoxy-4-iodoamphetamine-induced tic-like behaviors via its influences on the microbiota-gut-brain-axis. Brain Res Bull 153 , 59-73, doi :10.1016/j.brainresbull.2019.07.027 (2019).
2 Liu, YW, et al. Effects of Lactobacillus plantarum PS128 on Children with Autism Spectrum Disorder in Taiwan: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients 11 , doi:10.3390/nu11040820 (2019).
3 Chang, JS, et al. Probiotics Lactobacillus plantarum PS128 Intervention in Two Patients with Major Depressive Disorder. Taiwan J Psychiatry 33: 116-7, doi: 10.4103/TPSY.TPSY_22_19 (2019).
4 Huang, WC, et al. The Beneficial Effects of Lactobacillus plantarum PS128 on High-Intensity, Exercise-Induced Oxidative Stress, Inflammation, and Performance in Triathletes. Nutrients 11 , doi:10.3390/nu11020353 (2019).
5 Liu, WH, et al. Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ-free mice. Behav Brain Res 298 , 202-209, doi:10.1016/j.bbr.2015.10.046 (2016).
6 Liu, YW, et al. Psychotropic effects of Lactobacillus plantarum PS128 in early life-stressed and naive adult mice. Brain Res 1631 , 1-12, doi:10.1016/j.brainres.2015.11.018 (2016).
7 Liu, WH, et al. Genome architecture of Lactobacillus plantarum PS128, a probiotic strain with potential immunomodulatory activity. Gut Pathog 7 , 22, doi:10.1186/s13099-015-0068-y (201
